Discover the proven secret to healthy gums with PerioSciences Natural Oral Care System—simple, natural ingredients that instantly support your body's defenses.
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Non Toxic Body Approved ✪
✔︎ Ingredient Quality
9.78
✔︎ Results
9.53
✔︎ Enjoyment
8.87
✔︎ Value
8.87
✔︎ Sustainability
9.6
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This is a category, not a single product. Natural oral care systems often include a combination of products utilizing ingredients like: Baking Soda, Coconut Oil, Xylitol, Hydroxyapatite, Herbal Extracts (Neem, Turmeric), and Essential Oils.
*Ingredients may change. Please verify ingredients on product packaging.
The PerioSciences Natural Oral Care System, which is often a three-product set (toothpaste, rinse, and gel), is highly praised by users, many of whom were recommended it by their dentists. Customers consistently report excellent efficacy in reducing gum inflammation, sensitivity, and canker sores, often describing the results as "miraculous" or "works great." The formula is a major draw, being natural, alcohol-free, SLS-free, and focusing on a blend of patented antioxidants (Phloretin, Ferulic Acid, EGCG) and botanicals, although the lack of fluoride in the Natural version may not appeal to all. The minty taste is generally considered pleasant and non-burning. The primary downside is the high price point, which users acknowledge but often justify due to the superior results, especially for chronic oral health issues.
When you're trying to reduce toxins in your life, the products you put in your mouth matter just as much as what you eat. Your mouth is, after all, one of the most absorbent parts of your body. That's where the PerioSciences Natural Oral Care System comes in—a dentist-recommended trio of toothpaste, mouthwash, and dental gel that takes a refreshingly clean approach to oral wellness. Unlike conventional dental products packed with harsh chemicals and questionable ingredients, this natural oral care system harnesses the power of antioxidants to support your mouth's own healing abilities. Created by the same visionary who built SkinCeuticals (later acquired by L'Oréal), this innovative dental care collection represents a breakthrough in how we think about oral hygiene—not just killing bacteria, but nourishing your entire oral environment.
Russell Moon, the founder behind PerioSciences, previously co-founded SkinCeuticals in 1994, an antioxidant-based skincare company that was acquired by L'Oréal in 2005. After the success of SkinCeuticals, Moon founded PerioSciences in 2008, applying the same antioxidant science that revolutionized skincare to oral wellness.
Moon's philosophy is simple yet powerful: "The mouth is the gateway to the rest of the body. Not taking care of your mouth can have a substantial impact on the rest of your health." He saw how the dental industry focused primarily on killing harmful bacteria, but he knew there was a better way. The PerioSciences approach combines natural antibacterial ingredients with antioxidants to complement and amplify your body's biological systems.
Previously, PerioSciences products were sold exclusively to dental professionals, quickly becoming one of the most trusted brands among dentists with hundreds of customers. But Moon noticed inferior products flooding the consumer market with confusing claims. His mission became clear—he had to open PerioSciences directly to consumers so everyone could access these scientifically-backed oral care products.
The PerioSciences Natural Oral Care System stands apart because of what it doesn't contain. This fluoride-free, three-product dental care system combines antioxidant-based toothpaste, oral rinse, and dental gel for complete oral hygiene without the use of harsh chemicals. You won't find any seed oils or vegetable oils lurking in these formulas either—a critical distinction when you're trying to minimize inflammatory ingredients.
While the debate around seed oils continues, many health-conscious consumers are choosing to avoid them. Seed oils have high levels of omega-6 fats, which can lead to inflammation, and they're mostly used to make processed and ultra-processed foods. The PerioSciences natural oral care lineup keeps things clean and simple, focusing on ingredients your body can actually use.
This dental hygiene system is full of naturally-derived ingredients and does not contain fluoride, sodium lauryl sulfate, artificial sweeteners, or preservatives. When you're working hard to eliminate toxins from your environment, knowing exactly what you're putting in your mouth brings real peace of mind.
The PerioSciences approach to optimal care combines naturally-derived ingredients with antioxidants in the polyphenol family: Phloretin and Ferulic Acid. Think of it as adding a megadose of vitamins directly to your mouth.
Phloretin and Ferulic Acid have been shown in university-based studies to neutralize free radicals which lead to oxidative stress commonly caused by dental materials, alcohol, nicotine, and the hydrogen peroxide used in teeth whitening products. These antioxidants work together synergistically, meaning they're more powerful combined than they would be alone.
The toothpaste in the PerioSciences Natural Oral Care System contains additional beneficial ingredients. Key ingredients include Phloretin, Ferulic Acid, EGCG (a catechin found in green tea), Menthol/Peppermint Oil, Perilla Extract, Seabuckthorn Pulp Oil, Chamomile, and Hydroxyapatite. Each component plays a specific role in supporting your oral wellness.
The natural oral rinse features Ferulic Acid, EGCG, Tetrahydrocurcuminoids, Menthol/Peppermint Oil, Green Coconut Water, and Aloe Leaf Juice. These natural ingredients work together to create an environment where your mouth can thrive. The dental gel in this natural oral care collection rounds out the system with a concentrated dose of soothing antioxidants applied directly to your gums.
The ingredients in the PerioSciences Natural Oral Care System aren't just trendy botanicals—they're backed by research. EGCG, a catechin found in green tea, is shown in studies to combat oral plaque and bacteria, thus fighting bad breath. This means the natural oral care system addresses the root cause of odor, not just masking it with artificial fragrances.
Case studies reveal reduced inflammation and bleeding as well as accelerated wound healing in soft oral tissue when using these antioxidant-based products. This is particularly important after dental procedures, but it also benefits anyone dealing with sensitive or irritated gums.
Hydroxyapatite deserves special mention in the PerioSciences Natural Oral Care System. This naturally-occurring mineral is the main component of tooth enamel and has been shown to help remineralize teeth. Unlike fluoride, which works by creating a different type of crystal structure on your teeth, hydroxyapatite actually mimics your natural enamel. For those avoiding fluoride, this makes the natural oral care products especially appealing.
The PerioSciences dental care lineup also includes ingredients like Seabuckthorn Pulp Oil and Perilla Extract. These botanicals bring their own antioxidant and anti-inflammatory properties to support healthy gums and oral tissues. This fluoride-free three-product system goes beyond clean to freshen breath and nourish oral tissues with natural ingredients.
The PerioSciences Natural Oral Care System has built a loyal following, and the reviews speak volumes. One satisfied user shared: "The PerioSciences Sensitive Oral Care System actually improved the overall condition of my gums and sensitivity. I've been a faithful user twice a day and it offers round-the-clock relief."
Another customer reported: "Total health is important to me, so PerioSciences is the only toothpaste and mouth rinse I put into my body." This sentiment captures what many health-conscious consumers feel—when you're committed to reducing toxins, you want products you can trust completely.
The natural oral care gel receives especially enthusiastic praise. A reviewer noted: "I got the gel to use after I had teeth pulled. My gums felt great and it was very soothing." The immediate comfort this antioxidant oral care product provides makes it a favorite for post-procedure healing.
One user proclaimed: "HALLELUJAH. PerioSciences is the only product I've found that works! No more sensitivity and the canker sores are gone! I'm so thankful!" For people who've struggled with chronic oral issues, finding a natural solution that actually works feels like discovering a secret weapon.
The alcohol-free formula also wins fans. As one customer put it: "Great product! Alcohol free and a great taste. It doesn't burn your mouth like other mouth rinses." The PerioSciences dental care system proves that effective oral hygiene doesn't have to come with that harsh, burning sensation many conventional mouthwashes cause.
Even dental professionals recommend these natural oral care products. Users report: "My periodontist recommended that I use only this AO Pro Toothpaste for my gum issues. Has worked wonders, along with the dental gel." In fact, PerioSciences products are recommended by over 2,600 dentists.
Using the PerioSciences Natural Oral Care System is straightforward. The recommended routine involves using the oral care system as part of your routine twice daily. First, brush your teeth with the AO Pro Toothpaste. Next, rinse with one teaspoon of the AO Pro Rinse for up to one minute, then spit it out.
The final step in this natural oral care routine is what sets it apart. Apply a pea-sized amount of AO ProVantage Gel to your gums using your fingertip or a cotton swab, let the gel dissolve, then spit out excess. For best results, don't eat or drink for 30 minutes after applying the dental gel. This gives the antioxidants time to work their magic on your gum tissue.
The complete PerioSciences dental care system works synergistically—each product enhances the others. The toothpaste cleans and delivers antioxidants, the rinse extends that protection throughout your mouth, and the gel provides a concentrated treatment directly where your gums need it most.
PerioSciences is dedicated to quality research, with all products being the result of rigorous, scientific collaboration among scientists, biochemists, periodontists, dental and medical clinicians. Designed and tested in the university setting, these natural oral care products represent years of development.
The company's antioxidant research dates back more than 20 years, with Duke University testing showing strong anti-inflammatory results. Additional research at Baylor College of Dentistry and UNC Chapel Hill School of Dentistry confirmed that specific combinations of antioxidants neutralize free radicals and oxidative stress in the mouth.
Antioxidants naturally occur in saliva, and abnormally low levels of salivary antioxidants have been associated with oral diseases such as oral lichen planus, temporomandibular joint disorder, periodontal disease, and even oral cancer. By supplementing your mouth's natural antioxidant defenses, the PerioSciences Natural Oral Care System helps create an environment where oral tissues can stay healthy.
The natural ingredients in this dental care system aren't just thrown together—they're carefully formulated based on scientific understanding of how the mouth works. PerioSciences has worked with dentists for over 10 years to perfect their formulas containing scientifically proven ingredients that focus on the mouth's natural defense system.
The PerioSciences Natural Oral Care System represents a fundamental shift in how we approach dental hygiene. Instead of just attacking bacteria with harsh chemicals, this natural oral care collection works with your body's own systems. By providing antioxidants that support your mouth's natural defenses, these products help create lasting oral wellness rather than just temporary freshness.
For anyone committed to reducing toxins and supporting their body's natural healing abilities, the PerioSciences dental care lineup offers a simple yet powerful solution. The absence of seed oils, fluoride, sodium lauryl sulfate, and other questionable ingredients means you're getting pure, focused nutrition for your mouth. Combined with the founder's track record of success with SkinCeuticals and the backing of thousands of dental professionals, this natural oral care system has both the pedigree and the science to back up its claims.
Whether you're dealing with sensitivity, gum issues, or simply want to maintain optimal oral health, the PerioSciences Natural Oral Care System provides a clean, effective path forward. Your mouth truly is the gateway to your overall health—isn't it time you gave it the natural, antioxidant-rich care it deserves?
*AI Disclosure: This article was developed with the assistance of AI language models, which aided in research, drafting, and/or editing. We strive for accuracy, but AI-generated content can occasionally contain errors. We recommend you double-check and verify information before making decisions based on this content.
